The Anticancer Potential of Quassinoids-A Mini-Review

扫码查看

原文链接

NETL
NSTL
万方数据

外文摘要：The anticancer potential of quassinoids has attracted a great deal of attention for decades,and scientific data revealing their possible applications in cancer management are continuously increasing in the liter-ature.Aside from the potent cytotoxic and antitumor properties of these degraded triterpenes,several quassinoids have exhibited synergistic effects with anticancer drugs.This article provides an overview of the potential anticancer properties of quassinoids,including their cytotoxic and antitumor activities,mechanisms of action,safety evaluation,and potential benefits in combination with anticancer drugs.

外文关键词：

QuassinoidAnticancer potentialAntiproliferative mechanismSafety evaluationSynergistical combination with anticancer drugs

作者：

Cai Lu、Si-Nan Lu、Di Di、Wei-Wei Tao、Lu Fan、Jin-Ao Duan、Ming Zhao、Chun-Tao Che

展开 >

作者单位：

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resource Industrialization,Nanjing University of Chinese Medicine,Nanjing 210023,China

National and Local Collaborative Engineering Center of Chinese Medicinal Resource Industrialization and Formulae Innovative Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China

School of Chinese Medicine & School of Integrated Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China

School of Medicine & Holistic Integrative Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China

Department of Pharmaceutical Sciences,College of Pharmacy,University of Illinois Chicago,Chicago,IL 60612,USA

展开 >

基金：

National Natural Science Foundation of ChinaNatural Science Foundation of Jiangsu ProvinceNatural Science Foundation of Jiangsu Higher Education institutions of China

项目编号：

82274085BK2022047822KJB360010

出版年：

2024

DOI：

10.1016/j.eng.2023.11.022

工程(英文)

CSTPCDEI

ISSN：2095-8099

年,卷(期)：2024.38(7)