Research Advances on Biosynthetic Mechanism of Polymalic Acid by Aureobasidium Spp.
Polymalic acid(PMA)is a natural polyester material with advantages of high watersolubility,biocompatibility and non-immunogenicity,which has wide application prospects in biomedicine absorbent material and food industries.PMA was mainly synthesized by Aureobasidium spp.,the metabolic pathway,the key enzymes and the regulation metabolismin the biosynthesis of PMA were summarized in this review,and the research tendency of PMA biosynthesis metabolism was also proposed.