蟛蜞菊内酯药理作用及机制研究进展
Research Progress on Pharmacological Effects and Mechanisms of Wedelolactone
史欣悦 1赵梅玉 1周姝伶 1李海军 1石杰 1樊淑婷 1熊印华1
作者信息
- 1. 江西科技师范大学,江西 南昌 330013
- 折叠
摘要
作为天然香豆素类化合物的蟛蜞菊内酯具有多种药理活性,通过阅读近20 年国内外相关报道,发现蟛蜞菊内酯具有抗癌、抗肿瘤、抗炎、保肝、降血糖、降脂、治疗骨质疏松、促进称骨细胞、破骨细胞的生成等的药理作用,此文章系统的阐述了蟛蜞菊内酯药理作用的研究进展,目的在于为蟛蜞菊内酯的深入研究及其在中药中的合成及提取利用提供依据.
Abstract
As a natural coumarin compound,geniposide has a variety of pharmacological activities,and through reviewing domestic and international reports over the past 20 years,it has been found that geniposide possesses pharmacological effects such as anti-cancer,anti-tumor,anti-inflammatory,liver protection,blood sugar reduction,lipid-lowering,treatment of osteoporosis,promotion of osteoblast and osteoclast formation,etc.This article systematically elaborates on the research progress of the pharmacological effects of geniposide,with the aim of providing a basis for further research into geniposide as well as its synthesis and extraction for use in traditional Chinese medicine.
关键词
蟛蜞菊内酯/药理作用/抗炎作用/保肝作用/抗肿瘤作用Key words
wedelolactone/pharmacological effects/anti-inflammatory effect/hepatoprotective effect/antitumor activity引用本文复制引用
基金项目
江西省教育厅科学技术研究项目(GJJ2201313)
江西省高等学校精细化学品工程技术研究中心开放课题(JFCEC-KF-2202)
大学生创新创业训练计划(20231704202)
江西省研究生创新专项(2023)(YC2023-S910)
出版年
2024
NETL
NSTL
万方数据