Construction of a New Sensing Method Based on MXene-MB-cDNA Material for Cadmium Ion Detection
In this study,a novel competitive electrochemical sensor based on the transition metal carbide-methylene blue-complementary DNA probe(MXene-MB-cDNA)was developed for the detection of the heavy metal cadmium ion(Cd2+).The sensor is partially based on the MXene layered structure to enhance the MB loading rate,which amplifies the electrochemical detection signal;The other part involves using a Cd2+ Apt modified on the electrode as a linker to connect MXene-MB-cDNA.When Cd2+ is present,it competes with cDNA for binding to Apt,causing a change in the double-stranded structure and generating an electrochemical signal.The lowest detection limit is 0.034 mg·L-1 and it shows good linearity in the range of 0.01 to 1.6 mg·L-1(R2=0.991).Compared to traditional methods,this method is more simple and sensitive,providing a new approach for the detection of cadmium ions in research areas such as environmental protection,food safety,and biomedical sciences.
cadmium ionselectrochemical sensingtransition metal carbidesaptamers