Synthesis and Antibacterial Activities of Ruthenium Complexes Containing 3,5-di-butyric Phenyl Groups
A polypyridine ruthenium complexes were synthesized with 3,5-di-butyxyphenyl derivatives as the main ligand(DBPIP):Ru-1.The antibacterial activities of ruthenium complexes against S.aureus was evaluated by the minimum inhibitory concentration,time killing curve,biofilm experiments and drug resistance study experiments.The antibacterial activity of Ru-1 was investigated by the model of infection.The results showed that this ruthenium complexes showed excellent antibacterial activity against S.aureus.
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