Progress in the Reaction of Gem-Difluorocyclopropene
gem-Difluorocyclopropene can be efficiently synthesized by alkynes and difluorocarbon precursors in one step.In recent years,gem-difluorocyclopropene has attracted more and more attention from chemists,mainly because it can be used as an important synthon to synthesize a series of organic fluorides with important medicinal and agricultural values.Up to now,the summary of the synthesis and reaction progress of gem-difluorocyclopropene is still lacking.In this paper,the classical synthesis methods of gem-difluorocyclopropene and its progress and application in organic synthesis such as bifunctional reaction,nucleophilic substitution reaction,coupling reaction,electrophilic addition reaction and otherreactions are systematically summarized,which provides reference for the future chemical synthesis and reaction development of gem-difluorocyclopropene.
NETL
NSTL
万方数据
