高效液相色谱及其串联质谱技术在牙膏风险物质分析中的应用
Application of High Performance Liquid Chromatography and Tandem Mass Spectrometry in the Analysis of Risk Substances in Toothpaste
李静 1周智明 1陈张好1
作者信息
- 1. 广东省药品检验所 国家药品监督管理局化妆品风险评估重点实验室,广东 广州 510163
- 折叠
摘要
牙膏是日常生活中必不可少的口腔清洁护理用品,牙膏的基料较为复杂,牙膏中潜在的风险物质对人体存在一定危害,因此牙膏产品的安全性已成为当今社会关注的焦点之一.利用现代先进的检验检测技术对牙膏中潜在的风险物质进行分析、研究,将有利于实现对牙膏产品的安全监管,本文综述了近几年来高效液相色谱及其串联质谱技术在牙膏产品检验标准和检验方法开发等方面的研究以及应用进展,一定程度上能为牙膏产品的质量控制和科学监管提供参考.
Abstract
Toothpaste is an essential oral hygiene and care product in daily life.The base material of toothpaste is relatively complex,and the potential risk substances in toothpaste pose certain hazards to the human body.Therefore,the safety of toothpaste products has become one of the focuses of attention in today's society.The use of modern advanced inspection and detection technologies to analyze and study potential risk substances in toothpaste will be beneficial for achieving safety supervision of toothpaste products.This article reviews the research and application progress of high-performance liquid chromatography and its tandem mass spectrometry technology in the development of toothpaste product inspection standards and methods in recent years,which can provide reference for quality control and scientific supervision of toothpaste products to a certain extent.
关键词
高效液相色谱串联质谱法/牙膏/检测技术/风险物质Key words
high performance liquid chromatography tandem mass spectrometry/toothpaste/detection technique/risk substances引用本文复制引用
基金项目
广东省药品监督管理局科技创新项目(2022TDZ09)
广东省药品监督管理局科技引导扶持专项(2022YDZ04)
广东省药品监督管理局化妆品风险评估重点实验室专项(2021ZDZ03)
广东省中医药局面上项目(20221053)
出版年
2024
NETL
NSTL
万方数据