The Necessity Study of Introducing Halogen Bond in University Organic Chemistry Textbook
Halogen bond is an attractive noncovalent interaction that exists between molecules or within a molecule,and it has gradually become a hot topic in various fields of research,including chemistry,biology,materials,etc.In 2013,the International Union of Pure and Applied Chemistry(IUPAC)provided a clear definition of halogen bond.In many university organic chemistry textbooks,some significant organic reactions involve the participation of halogen molecules.Through quantum chemical calculations,we have demonstrated the presence of halogen bond in these organic reactions involving halogen molecules,emphasizing that introducing the concept of halogen bond in textbooks is beneficial for students to gain a more accurate understanding and proficient mastery of these important reactions.