Based on 5AR Activity Test Screening Oil Control Raw Materials for Cosmetics
In this paper,the inhibition rate of 5AR activity was used to evaluate the oil control effect of cosmetic raw materials.At a test concentration of 1%,Backhousia Citriodora extract,Epilobium Angustifolium extract,Trifolium Pratense extract,Sophora Flavescens extract,and zinc-enriched yeast all had effects on 5AR,with an inhibition rate of 22.29%～55.28%,among which zinc-enriched yeast has the best effect,with an inhibition rate of 55.28%.Under the condition of 5%sample concentration,Melaleuca Alternifolia hydrosol,Rosmarinus Officinalis hydrosol,Lavandula Angustifolia extract,Rosmarinus Officinalis extract,and Hamamelis Virginiana extract had effects on 5AR with inhibition rate ranged from 48.24%to 68.34%,with Hamamelis Virginiana extract and Lavandula Angustifolia extract having relatively better effects,with inhibition rates of 68.34%and 60.00%,respectively.Under the 0.5%concentration test,azelaic acid and citric acid monohydrate showed very good effects on 5AR inhibition rate reached over 90%,95.29%and 92.36%,respectively.Plant compound tannic acid,lactobionic acid and gluconolactone have a significant effect on 5AR is relatively weak,with inhibition rates of 51.38%,65.33%,and 44.27%,respectively.
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