In this paper,the inhibition rate of 5AR activity was used to evaluate the oil control effect of cosmetic raw materials.At a test concentration of 1%,Backhousia Citriodora extract,Epilobium Angustifolium extract,Trifolium Pratense extract,Sophora Flavescens extract,and zinc-enriched yeast all had effects on 5AR,with an inhibition rate of 22.29%~55.28%,among which zinc-enriched yeast has the best effect,with an inhibition rate of 55.28%.Under the condition of 5%sample concentration,Melaleuca Alternifolia hydrosol,Rosmarinus Officinalis hydrosol,Lavandula Angustifolia extract,Rosmarinus Officinalis extract,and Hamamelis Virginiana extract had effects on 5AR with inhibition rate ranged from 48.24%to 68.34%,with Hamamelis Virginiana extract and Lavandula Angustifolia extract having relatively better effects,with inhibition rates of 68.34%and 60.00%,respectively.Under the 0.5%concentration test,azelaic acid and citric acid monohydrate showed very good effects on 5AR inhibition rate reached over 90%,95.29%and 92.36%,respectively.Plant compound tannic acid,lactobionic acid and gluconolactone have a significant effect on 5AR is relatively weak,with inhibition rates of 51.38%,65.33%,and 44.27%,respectively.