Study on Quality Evaluation and Repair Efficacy of Compound Oil Nanoemulsion
In this study,the polyglycerol emulsifier was selected as the main emulsifier,glycerin was used as the co-emulsifier,and three kinds of plant oils(paeonia suffruticosa seed oil∶carthamus tinctorius seed oil∶crambe abyssinica seed oil=1∶1∶1)were used as the encapsulated actives.The nanoemulsion of three plant oils was prepared by high-pressure homogenization technology,and its physical and chemical properties were investigated.Tindal phenomenon proves the nanoemulsion is an oil-in-water emulsion.The nanoemulsion particle diameter(D90)is 129 nm,PDI is 0.183,and the Zeta potential is-33.37 mV,which meet the basic requirements of nanoemulsion.At the same time,the nanoemulsion show excellent dilution stability,with conductivity of 22.04 μs/cm,pH of 7.05,refractive index of 1.4312 and viscosity of 57.11 mpas.By sensory evaluation,the serum within 5%nanoemulsion of three kind of plant oils is better than the blank control,including testing indexes of moisturizing,hydrating,softness and so on.By human efficacy evaluation test,when applying the serum within 5%nanoemulsion for 4 h and 6 h,the skin hydration is respectively improved by 32.97%and 34.47%,and the TEWL is respectively improvedby 26.80%and 30.52%,with better performance compared to the control(p＜0.05),which indicates the skin repair is accelerated.
NETL
NSTL
万方数据
