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莽草酸印迹聚合物的微流控合成及性能研究

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本研究通过微流控技术成功合成了莽草酸印迹聚合物。通过傅立叶红外吸收光谱(FT-IR)和扫描电子显微镜(SEM)对聚合物进行表征,考察了微流控印迹聚合物(Mic-MIP)与常规合成的印迹聚合物(Con-MIP)吸附效果比较的实验、平衡吸附实验、吸附动力学实验和吸附选择性实验。结果表明,Mic-MIP比Con-MIP具有更高的吸附量和印迹因子,通过Langmuir拟合得到Mic-MIP的最大吸附量为5。18 μg/mg,吸附动力学实验中发现Mic-MIP更符合准二阶动力学模型,在吸附选择性实验中体现出了Mic-MIP的高特异性识别能力。
Microfluidic Synthesis and Properties of Shikimic Acid Imprinted Polymer
In this study,shikimic acid imprinted polymer was successfully synthesized by microfluidic technology.The polymer was characterized by Fourier transform infrared spectroscopy(FT-IR)and scanning electron microscopy(SEM).The experiments of comparing the adsorption effect of microfluidic imprinted polymer(Mic-MIP)and conventional synthesized imprinted polymer(Con-MIP),equilibrium adsorption experiment,adsorption kinetics experiment and adsorption selectivity experiment were investigated.The results showed that Mic-MIP had higher adsorption capacity and imprinting factor than Con-MIP,and the maximum adsorption capacity of Mic-MIP was 5.18 pg/mg by Langmuir fitting.In the adsorption kinetic experiment,it was found that Mic-MIP was more in line with the Pseudo-second-order model,the high specific recognition ability of Mic-MIP was demonstrated in the adsorption selectivity experiment.

microfluidicshikimic acidmolecularly imprinted polymeradsorption enrichment

贾明之、孟鑫、赵丽丽、黄艳萍、刘照胜

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天津医科大学药学院,天津 300070

天津市临床药物关键技术重点实验室,天津 300070

微流控 莽草酸 分子印迹聚合物 吸附富集

天津市自然科学基金重点项目

19JCZDJC36400

2024

广东化工
广东省石油化工研究院

广东化工

影响因子:0.288
ISSN:1007-1865
年,卷(期):2024.51(6)
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