中高能重离子束全径迹辐照材料和细胞的实验装置设计及效应分析
Experimental Design and Effects Analysis of Full-Track Irradiation Materials and Cells Using Mid-high Energy Heavy Ion Beams
李兴林 1曲颖 2孙曙光3
作者信息
- 1. 天津科技大学,天津 300457
- 2. 中国科学院近代物理研究所,甘肃 兰州 730000
- 3. 安徽思母塘生物技术发展有限公司,安徽 马鞍山 243000
- 折叠
摘要
中高能重离子束注入生物材料的径迹显著深于生物靶,且不同径迹点上的剂量分布、理化效应等又大不相同,所以,同一靶点通常不可能接受所有理化因子的作用(即全径迹辐照).本实验设计思路:基于CR-39 核径迹探测手段,在纯水介质中验证全径迹辐照综合效应特征;通过沿径迹上连续逆向移动靶材料或细胞培养液,以探究全径迹的辐照效应.最后,与对照组相比较,揭示重离子束全径迹的辐照效应及其潜在的分子改性、细胞改良和发酵工程等方面的应用价值.
Abstract
On the one hand,both the track of med-high energy heavy ion beams implanted into biological materials is significantly deeper than that of target materials,on the other hand,the dose distribution and physic-chemical effects at different track points are quite different,so it is usually impossible for the same target point to accept irradiation form all physical and chemical effects(ie full-track irradiation).The design concept of this experiment is:based on the CR-39 nuclear track detection method,verify the comprehensive effect characteristics of full-track irradiation in pure water medium;and exploring the irradiation effect of the full-track by continuously moving target materials or cells in the opposite direction along the track.Finally,compared with the control groups,the full-track irradiation effect of heavy ion beams and its potential application value were revealed such as molecular-modification,cell improvement and ferment engineering.
关键词
重离子束/全径迹辐照/材料/细胞/装置设计/效应分析Key words
heavy ion beams/full-track irradiation/materials/cells/experimental design/effect analysis引用本文复制引用
基金项目
中国科学院兰州重离子加速器国家实验室培育项目(HIR2021PY013)
出版年
2024
NETL
NSTL
万方数据