首页|鞣花酸对胃癌细胞生长及迁移的作用研究

鞣花酸对胃癌细胞生长及迁移的作用研究

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目的:探讨鞣花酸对胃癌细胞BGC823 的生长及迁移能力的影响.方法:体外培养BGC823 细胞,采用MTT法检测细胞活力;采用相差显微镜观察细胞形态;采用细胞划痕实验观察细胞的迁移能力.结果:鞣花酸可显著降低 BGC823 细胞活力;经鞣花酸干预后,细胞皱缩,细胞碎片增加;鞣花酸可降低BGC823 细胞的迁移能力.结论:鞣花酸对BGC823 细胞具有明显的抑制生长及迁移的作用.
Studies on the Effect of Ellagic Acid on the Growth and Migration of Gastric Cancer Cells
Objective:To investigate the effects of ellagic acid on the growth and migration ability of gastric cancer cells BGC823.Methods:BGC823 cells were cultured in vitro,and cell viability was detected by MTT assay;cell morphology was observed by phase contrast microscopy;and cell migration ability was observed by cell scratch assay.Results:Ellagic acid significantly reduced the viability of BGC823 cells;after intervention with ellagic acid,the cells were wrinkled and the cellular debris increased;ellagic acid reduced the migration ability of BGC823 cells.Conclusion:Ellagic acid has a significant inhibitory effect on the growth and migration of BGC823 cells.

gastric cancer cellsellagic acidmigrationgrowthBGC823 cells

李色杰、梁锦、罗清淋、黄龙江、郑广进、黄桔

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广西民族师范学院 化学与生物工程学院,广西 崇左 532200

胃癌细胞 鞣花酸 迁移 生长 BGC823细胞

自治区级大学生创新创业训练计划立项项目(2023)

S202310604137

2024

10.3969/j.issn.1007-1865.2024.07.022

广东化工
广东省石油化工研究院

广东化工

影响因子：0.288
ISSN：1007-1865
年,卷(期)：2024.51(7)
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