Study on Synthesis and DPPH Free Radical Scavenging Activity of Schiff Base Containing Quinoline-Heterocyclic Ring
Three hydrazone Schiff bases containing quinoline heterocyclic rings were synthesized from salicylaldehyde derivatives(salicylaldehyde,5-methyl-salicylaldehyde and 5-methoxy-salicylaldehyde)and 2-hydrazine-quinoline.[L1=salicylaldehyde-2-hydrazinoquinoline,L2=5-methyl salicylicaldehyde-2-hydrazinoquinoline,L3=5-methoxy-salicylaldehyde-2-hydrazinoquinoline].The structures were characterized by IR,Uv-Vis absorption spectroscopy,mass spectrometry and NMR spectroscopy.DPPH radical method was used to test their antioxidant activity,and the effects of solvent,temperature and light on scavenging DPPH free radical activity were also investigated.The results showed that the three kinds of Schiff bases containing quinoline heterocyclic rings had good scavenging ability for DPPH free radicals with ethanol as solvent,and temperature and light had little influence on the scavenging effect.
quinoline heterocyclic ringschiff basesynthesisscavenging activity of DPPH free radical
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