Exploratory Organic Chemistry Experimental Teaching——Taking the Synthesis of 2-Amino-5-Ethyl-1,3,4-Thiadiazole as an Example
Organic chemistry experiments are one of the important foundational courses in pharmaceutical engineering,which not only supplement the theoretical courses of organic chemistry,but also serve as the foundation for studying pharmaceutical courses.This article uses aminothiourea and propionaldehyde as raw materials,and selects the optimal reaction conditions by changing the solvent,oxidant type,reaction temperature,reaction time,and reactant feed ratio to improve the yield of 2-amino-5-ethyl-1,3,4-thiadiazole.Through this experiment,it is not only beneficial for students to consolidate theoretical knowledge,improve their hands-on ability in experiments,but also to cultivate their love for chemistry,scientific research,and stimulate exploratory thinking,which plays an important role.
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