Quinolones are a class of drugs widely used in the field of antimicrobial.Because of the antibacterial activities,can effectively inhibit a variety of bacterial infections.Quinolones are widely used in the treatment of upper respiratory tract infections,lower respiratory tract infections,urinary tract infections,skin and soft tissue infections,and digestive tract infections.However,quinolones also have some side effects and resistance issues that need attention.In this paper,the chemical structure,antibacterial spectrum and antimicrobial mechanism of quinolones were introduced.At the same time,the development trend of quinolones including the research and development of new quinolones,the application of quinolones in antibacterial combination therapy and the prospect of clinical therapy were also prospected.
quinolonesantimicrobial drugsbactericidal broad-spectrumdrug resistancedrug development
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