Study on the Effect of High-temperature Instant Sterilization Process on the Quality of Herbal Powder of Andrographis Paniculata
Objective:To study the influence of high-temperature instant sterilization process on the quality of traditional Chinese medicine Andrographis paniculata powder.Method:The factors of sterilization temperature and time were studied,and the moisture,andrographolide,neoandrographolide,14-deoxyandrographolide,dehydrated andrographolide and other effective components were detected and compared before and after sterilization.The influence of sterilization process on the quality of Andrographis paniculata powder was evaluated,providing reference for the production process of sterilization.[Result]After high-temperature instant sterilization,the moisture and total number of colonies decreased significantly,while the identification items and effective component content did not change significantly.The stability test results also showed that the lactone content of the samples was stable,and microbial limits were no significant change after high-temperature instant sterilization in 12 months.The optimal sterilization production process was obtained as following:sterilization temperature 185℃,sterilization time 15 s.Conclusion:After high-temperature instant sterilization of Andrographis paniculata powder,the microbial killing effect is obvious,while there was had no effect on the quality.The results would provide experimental basis for the application of high instantaneous temperature sterilization technology in Andrographis paniculata sterilization.
high temperature instantaneous sterilizationmicrobial limitsAndrographis paniculata powderquality evaluation
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