Integrating Frontier Scientific Research into Applied Chemistry Comprehensive Experimental Teaching:Preparation of New Silica Crosslinked Micelle Core-shell Nanoparticles and Its Application in Drug Delivery
A comprehensive undergraduate chemistry experiment was designed for the synthesis,characterization,and application of a new type of silica cross-linked micelle core-shell nanoparticles.Firstly,a silicon source is added during the self-assembly process of the polymer to form micelles,which is cross-linked with silica to form core-shell nanoparticles with a water-soluble shell and a lipophilic core.Then,curcumin drugs are loaded onto the lipophilic inner shell.Finally,drug release studies are conducted on the loaded curcumin nanoparticles.This experiment can broaden students'research horizons,familiarize them with the synthesis methods and application values of nanomaterials,and the abilities of practical operation in preparing nanomaterials,laying a solid foundation for their future scientific research and practical applications.
core-shell nanoparticlecurcumindrug deliveryexperimental teachingfrontier scientific research
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