Research Development on the Surface Modification of Anticoagulant Coating in Oxygenator
Oxygenator is one of the vital components of respiratory support devices.As the core of the membrane oxygenator,the blood compatibility on the surface of the membrane material is very important,which directly affects the service life of the oxygenator and can reduce the possibility of complications.Hollow fiber membrane can reduce the blood volume in vitro,and possesses excellent oxygen and carbon dioxide exchange function in the blood,so it is widely used in oxygenators.In this review,the types and applications of membrane materials in membrane oxygenator,as well as the current development and research progress of surface modification of anticoagulant coating have been summarized.It is thought that this review will provide references for the study of coating materials on the surface of artificial membrane lung.