Using peony seed oil as experimental material,UV irradiation was used to simulate the in vitro photoaging environment of 3D skin model,and the anti-photoaging efficacy of peony seed oil was verified by detecting the content of Reactive Oxygen Species,the expression of collagen Ⅳ and the positive cell rate of cyclobutanepyrimidinemer,a DNA damage index,through the effect of peony seed oil.The results showed that peony seed oil could significantly reduce the content of ROS(p＜0.01)and increase the collagenⅣ content(P＜0.01)in skin after UV irradiation,while the CPD positive cell rate decreased significantly(P＜0.01).The experiment shows that peony seed oil can significantly reduce the content of ROS,improve the content of collagen Ⅳ in skin after UV irradiation,and reduce the rate of CPD positive cells,thus playing a certain anti-photoaging effect on skin.
维普
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