Evaluation for Anti-photo aging Efficacy of Peony Seed Oil by 3D Skin Model
Using peony seed oil as experimental material,UV irradiation was used to simulate the in vitro photoaging environment of 3D skin model,and the anti-photoaging efficacy of peony seed oil was verified by detecting the content of Reactive Oxygen Species,the expression of collagen Ⅳ and the positive cell rate of cyclobutanepyrimidinemer,a DNA damage index,through the effect of peony seed oil.The results showed that peony seed oil could significantly reduce the content of ROS(p＜0.01)and increase the collagenⅣ content(P＜0.01)in skin after UV irradiation,while the CPD positive cell rate decreased significantly(P＜0.01).The experiment shows that peony seed oil can significantly reduce the content of ROS,improve the content of collagen Ⅳ in skin after UV irradiation,and reduce the rate of CPD positive cells,thus playing a certain anti-photoaging effect on skin.
万方数据
维普
