Research Progress of Ginsenoside CK Activity and Biotransformation Synthesis
Ginsenoside CK(Compound K)belongs to the rare ginsenosides,which is the main metabolite obtained from natural diol-type ginsenosides by intestinal microbial transformation,and is almost nonexistent in natural ginseng herbs,and it has a unique chemical structure and pharmacological activity,and has shown a high degree of safety in the areas of anticancer,anti-inflammation,antidiabetic,regulation of the nervous system,antiangiogenesis,and antiaging,and a high degree of diversity biology.Ginsenoside CK is highly absorbed in the human body,but the production technology and cost are high.The synthesis of ginsenoside CK by an efficient biotransformation method will further enhance its application value in the field of drug discovery and expand the application of ginsenoside CK in the field of drugs and great health.This paper reviews the research progress of ginsenoside CK pharmacological activity and bioconversion synthesis studies,with a view to providing reference for the production and application of ginsenoside CK.