The study utilized natural macromolecular Bletilla striata polysaccharide as a raw material to synthesize a novel polypolysaccharide hydrogel with excellent biocompatibility,strong adhesion,and wound healing properties through Schiff base reaction with cationic polymer polyethylenimine(PEI).The structure of the hydrogel was characterized using FT-IR,while SEM was employed to analyze its microscopic morphology.The adhesive,healing,and injectable properties of the hydrogel were investigated.Results demonstrated that Bletilla striata polysaccharide reacted with PEI containing amino groups on its surface to rapidly form a gel via Schiff base reaction.The resulting hydrogel exhibited a porous network structure along with remarkable adhesion,injectability,and self-healing capabilities.These findings suggest that this new gel formulation holds great potential as a safe and effective excipient for wound care applications.
关键词
创面护理凝胶/白芨多糖/聚乙烯亚胺/席夫碱
Key words
wound care gel/bletilla striata polysaccharide/polyethylenimine/schiff base