首页|白藜芦醇应用于消化道肿瘤治疗中的研究进展

白藜芦醇应用于消化道肿瘤治疗中的研究进展

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消化道肿瘤是全球癌症相关死亡的主要原因之一.环境、饮食和生活方式因素以及家族史是消化道肿瘤最重要的危险因素.尽管目前的肿瘤治疗方法(包括手术、化疗和放疗)有所改善,但由于诊断延迟、复发和药物副作用,晚期消化道肿瘤患者的生活质量仍然较差.因此,迫切需要寻找新的治疗策略来提高患者的治疗效果和生存率.白藜芦醇(Res)具有多种有价值的药理作用,包括抗氧化、抗炎、抗癌、抗菌和心血管保护作用,迄今为止,Res在预防和治疗消化道肿瘤中的多种抗癌分子机制涉及其作用的多种途径,包括氧化应激、细胞增殖和细胞凋亡.
Research Progress on the Application of Resveratrol in the Treatment of Digestive Tract Tumors
Digestive tract tumors are one of the leading causes of cancer-related deaths worldwide.Environmental,dietary and lifestyle factors,as well as family history,are the most important risk factors for GI tumors.Despite improvements in current oncological treatments(including surgery,chemotherapy and radiotherapy),the quality of life of patients with advanced GI tumors remains poor due to delayed diagnosis,recurrence and drug side effects.Therefore,there is an urgent need to find new therapeutic strategies to improve patient outcomes and survival.Resveratrol(Res)has a variety of valuable pharmacological effects including antioxidant,anti-inflammatory,anticancer,antimicrobial,and cardiovascular protective effects,and to date,multiple anticancer molecular mechanisms of Res in the prevention and treatment of gastrointestinal tumors involve a variety of pathways of its action,including oxidative stress,cell proliferation,and apoptosis.

resveratrolgastrointestinal tumorsclinical experimentssynthetic process

陈怡、朱艳丽、徐霄航、李姣姣、杨健华、左旭阳

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佳木斯大学,黑龙江 佳木斯 154007

佳木斯大学附属第一医院消化二科,黑龙江 佳木斯 154002

白藜芦醇 消化道肿瘤 临床实验 合成过程

2024

广东化工
广东省石油化工研究院

广东化工

影响因子:0.288
ISSN:1007-1865
年,卷(期):2024.51(16)