Optimization of Extraction Process for Wuwei Zhenju Tablets by Orthogonal Experimental Method
Article takes the optimal extraction process of Wuwei Zhenju tablets as the research and development basis for Wuwei Zhenju tablets.Method:Orthogonal experiments were conducted using total flavonoid extraction and total anthraquinone extraction as indicators to investigate the effects of water addition,extraction time,and extraction frequency on the water extraction process,as well as the effects of relative density,alcohol precipitation concentration,and alcohol precipitation time on the alcohol precipitation process.Result:The optimal preparation process for Wuwei Zhenju tablets is to add 12 times the amount of water,extract 3 times,each time for 1.5 hours,concentrate the water extract to a relative density of 1.080~1.129(60℃),with an alcohol precipitation concentration of 65%and an alcohol precipitation time of 24 hours.Conclusion:The optimized extraction process is reasonable and stable,with the characteristics of easy operation,good controllability,and good repeatability,which can provide a theoretical basis for the development of Wuwei Zhenju tablets.
Wuwei Zhenju tabletextraction processorthogonal test