Review on the Deacetylation Degree and Substitution Degree of Carboxymethyl Chitosan
With the wide application of CMCS(carboxymethyl chitosan)as biomaterials in the medical instrumentation industry,it is urgently needed for get an effective method to determine DD(the degree of deacetylation)and DS(degree of substitution).At the same time,there are problems such as incomplete detection techniques for the DD and DS of CMCS,and insufficient detection methods.Therefore,this article briefly described the principles and methods of ash analysis,colloidal titration,NMR,FT-IR,potentiometric titration,conductance titration,HS-GC,analyzed and discussed the advantages and disadvantages of each method.Finally,the study prospect of DD and DS values of CMCS by HS-GC is prospected.With the in-depth and extensive development of this method,it can further promote the development of quality evaluation technology for CMCS.
carboxymethyl chitosandegree of deacetylationdegree of substitutionHS-GC
万方数据
维普
