首页|HPLC法检测儿童化妆品中40种防腐剂及结果分析

HPLC法检测儿童化妆品中40种防腐剂及结果分析

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为了解儿童化妆品中防腐剂的使用情况,以期为儿童化妆品中防腐剂的安全风险和限度研判提供数据支持.本次对市售的222 批次儿童化妆品开展 40 种防腐剂检测,以《化妆品安全技术规范》(2015 年版)第四章 4.1 甲基异噻唑啉酮等 23 种组分和 4.2 吡硫鎓锌等19 个组分为检测依据,并对结果进行了统计分析.结果显示,222 批次儿童化妆品中检出 11种常用防腐剂,检出频次最高的为苯氧乙醇(56.3%)和羟苯甲酯(55.4%).单一产品检出两种及两种以上的防腐剂占比62.2%,有少数产品检出5~6 种防腐剂.本次检出的防腐剂含量均符合《化妆品安全技术规范》(2015 年版)标准规定,但检出结果与产品标签标示一致率仅为 28.8%.结论:目前儿童化妆品中防腐剂多采用复配体系,防腐剂标签标示不符问题较为严重,提示监管部门应当加强标签标示管理,保障儿童的用妆安全.
Determination of 40 Preservatives in Children's Cosmetics by HPLC and Analysis of the Results
Preservatives are substances added to cosmetics for the purpose of promoting the growth of microorganisms.However,preservatives may lead to skin allergies.In order to investigate the addition of preservatives in children's cosmetics,which is expected to accumulate scientific data for the safety monitoring and limit assessment of preservatives in children's cosmetics.40 preservatives were detected for 222 batches of children's cosmetics based on the methods specified in Chapter 4.1 and Chapter 4.2 in the"Safety and Technical Standards for Cosmetics"(2015 edition).The results were statistically analyzed.The results showed that 11 preservatives were detected in 222 batches of children's cosmetics,which the most frequently detected preservatives are phenoxyethanol(56.3%)and methylparaben(55.4%).62.2%detected two or more types of preservatives in a single product,with a few products detecting 5-6 types of preservatives.The content of preservatives detected in 222 batches of children's cosmetics conforms to the requirement of"Cosmetic Safety Technical Specification"(2015 edition),but the consistency rate between the detection results and the product label labeling is only 28.8%.At present,preservatives in children's cosmetics mostly use compound systems.There are situations which the actual measurement results are not completely consistent with the labels of cosmetic preservatives.It is urgent to strengthen label and identification management to ensure the safety of children's cosmetics.

HPLCchildren's cosmeticspreservativesafety monitoringlabeling

赵倩茹、孟雅萍、刘骅、高瑞芳、卫星红、李祥胜

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安徽省食品药品检验研究院,安徽 合肥 230051

高效液相色谱法 儿童化妆品 防腐剂 安全风险监测 标签标示

安徽省药品监督管理局科技创新项目

AHYJ-KJ-202216

2024

广东化工
广东省石油化工研究院

广东化工

影响因子:0.288
ISSN:1007-1865
年,卷(期):2024.51(20)