Comparison of Two Methods for Determining the Content of Aspirin Enteric-coated Tablets in Teaching Applications
Determining the content of aspirin enteric-coated tablets is the core teaching content of pharmaceutical analysis experiments.Two-step acid-base titration and high-performance liquid chromatography are the two most commonly used methods in teaching experiments.This study compares experimental principles,methods,experimental facilities,and teaching practice capabilities from many aspects.The two-step acid-base titration method has the characteristics of easy experimental operation and less experimental equipment required,but the measurement results are not accurate enough.The high-performance liquid chromatography method provides accurate measurement results and can improve students'ability to use high-performance liquid chromatography.However,the experimental process is complex and has high requirements on experimental space and funding.Finally,it is proposed to use the two-step acid-base titration method as the basic teaching content and high-performance liquid chromatography as the expanded content.While understanding the principles and methods of determining the content of aspirin enteric-coated tablets,we will improve students'ability to apply modern drug analysis equipment and improve the level of talent training.
drug analysisexperimental teachingtwo step acid-base titration methodHPLCteaching reform
万方数据
维普
