固相萃取-气相色谱串联质谱法测定生活饮用水中8种亚硝胺类化合物
Determination of Nitrosamines in Drinking Water by Solid Phase Extraction Gas Chromatography/Tandem Mass Spectrometry
张祥汉 1冯冬雪 2钟建军 1冯秋仪 1秦伟1
作者信息
- 1. 珠海市供水与排水治污中心,广东 珠海 519000
- 2. 广东实朴检测服务有限公司,广东 广州 510000
- 折叠
摘要
近年来,含氮消毒副产物由于高遗传病毒性而被人们广泛认识,典型 N-DBPs 卤乙腈和亚硝胺类(NAs)已经被多个国家或组织纳入饮用水水质标准.为准确检测生活饮用水中的亚硝胺类化合物,本研究采用固相萃取法处理生活饮用水,用气相色谱-串联质谱仪测定生活饮用水中8 种亚硝胺类化合物,通过优化固相萃取条件及气质联用仪的分析测定条件,使方法在25 μg/L～625 μg/L范围内线性良好.检出限和定量限分别为1.44 ng/L～4.20 ng/L,空白水样未检出,水样加标回收率为81.3%～114%,方法的精密度和准确度良好.此优化方法适用于生活饮用水中8 种常见亚硝胺类化合物的检测.
Abstract
In recent years,nitrogen containing disinfection by-products have been widely recognized due to their high genetic and viral properties.Typical N-DBPs haloacetonitrile and nitrosamines(NAs)have been included in drinking water quality standards by multiple countries or organizations.In order to accurately detect nitrosamine compounds in drinking water,this study used solid-phase extraction to treat drinking water and determined 8 nitrosamine compounds in drinking water using gas chromatography-tandem mass spectrometry.By optimizing the solid-phase extraction conditions and the analysis and determination conditions of the gas chromatography-mass spectrometer,the method was optimized good linearity within the range of 25 μg/L～625 μg/L.The detection limit and quantification limit are 1.44 ng/L～4.20 ng/L,respectively.The blank water sample was not detected,and the recovery rate of water sample spiking was 81.3%～114%.The precision and accuracy of the method are good.This optimization method is applicable for the detection of 8 common nitrosamine compounds in drinking water.
关键词
亚硝胺类/固相萃取/气相色谱-串联质谱法/生活饮用水Key words
nitrosamines/solid phase extraction/gas chromatography-tandem mass spectrometry/domestic drinking water引用本文复制引用
出版年
2024
NETL
NSTL
万方数据