Research Progress of Magnetic Nano-liposomes in Cancer Diagnosis and Treatment
Magnetic nanoliposomes(MNL)is a new type of agent in which magnetic nanoparticles are added to liposomes to make them targeted,and in recent years,it has been widely used in the diagnosis and treatment of cancer because of its excellent biocompatibility and and highly targeted nature.Cancer cells are usually more sensitive to heat than normal cells,MNL can be used as a heating agent,which can be introduced into the tumour site to increase the local temperature,induce apoptosis or change the proliferation and differentiation of cancer cells.MNL enters the body with blood circulation under the effect of applied magnetic field,and targets the cancer site,and through the positioning of infrared and other technologies,the drugs contained therein are targeted to play a role in the treatment,and have lower toxicity and side-effects compared to chemotherapy.nanocarriers with lipid bilayers,they are becoming more and more important in cancer therapy due to their excellent biocompatibility.In this paper,we briefly summarise the composition and preparation methods of liposomes,magnetic nanoparticles and magnetic nanoliposomes,and provide a review on their research progress in cancer diagnosis and treatment.