首页|乳腺癌患者化疗前后血清Ca、P、Mg、Zn含量与疗效的关系

乳腺癌患者化疗前后血清Ca、P、Mg、Zn含量与疗效的关系

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目的 探讨乳腺癌患者化疗效果对血清中钙(Ca)、磷(P)、镁(Mg)以及锌(Zn)含量的影响.方法 选取普宁市人民医院进行化疗的乳腺癌患者80例作为化疗组,观察患者化疗前后血清中Ca、P、Mg以及Zn的水平变化,另选80例健康女性作为健康人组,检测其血清Ca、P、Mg、Zn水平,并进行对比分析.结果 化疗组Ca、Mg含量明显低于健康人组(P<0.05),Zn含量明显高于健康人组(P<0.05),P含量与健康人组相比无统计学意义(P>0.05);化疗后Ca、Mg含量显著高于化疗前(P<0.05),Zn含量显著低于化疗前(P<0.05),P含量略低于化疗前(P>0.05).结论 血清Ca、P、Mg、Zn含量随着临床治疗效果所变化,可作为检测化疗效果的有效反应因子,在疗效判定方面具有一定的参考价值.
Breast Cancer Before and After Chemotherapy in Patients with Serum Ca, P, Mg, the Relationship Between Zinc Content and Curative Effect
Objective To study the effect of breast cancer patients with chemotherapy on serum calcium (Ca), phosphorus (P) and magnesium (Mg) and the influence of content of zinc (Zn).Methods Choose 80 cases on the chemotherapy of breast cancer patients as chemotherapy group, were observed before and after chemotherapy in patients with serum Ca, P, Mg and zinc level changes, choose 80 cases of healthy women as healthy people group, detect the serum Ca, P, Mg, zinc levels, and comparison analysis.Results Chemotherapy group, Ca, Mg content significantly lower than the healthy group (P<0.05), zinc content is significantly higher than the healthy group (P<0.05), P content in comparison with healthy group had no statistical significance (P>0.05);Ca, Mg content were significantly higher after chemotherapy before chemotherapy (P<0.05), the zinc content is significantly lower than before treatment (P<0.05), the P content is slightly lower than before treatment (P>0.05).Conclusion Serum Ca, P, Mg and zinc content changes as the clinical therapeutic effect, can be used for effective detection of chemotherapy response factors, in terms of outcome has a certain reference value.

serum trace elementsbreast cancerchemotherapyimpact

林长裕

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普宁市人民医院,普宁 515300

血清微量元素 乳腺癌 化疗 影响

2017

广东微量元素科学
广东省科学技术情报研究所 广州地区微量元素与健康研究会 广州市微量元素研究所

广东微量元素科学

影响因子:0.355
ISSN:1006-446X
年,卷(期):2017.24(5)
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