Study on the Expression Pattern of IGF and IGF-IR Genes in Early Hepatic Development of Cherry Valley Broiler Ducks
Cherry Valley broiler duck is a world-renowned lean duck,and its liver development is crucial for the health and growth of the organism.The aim of this study was to investigate the liver development and key gene expression patterns of Cherry Valley ducks in the late embryonic and early emergence stages using the Cherry Valley duck as an experimental model.One hundred and twenty fertilized duck eggs were used in the experiment,and the changes in body weight and liver weight were recorded at the 16th,21st,and 28th embryonic ages,and at the 7th,14th,and 21st day of age.The expression of IGF1,IGF2,and IGF-ⅠR mRNAs related to liver development were detected by fluorescence quantitative PCR.The results showed that IGF1,IGF2 and IGF-ⅠR had been expressed in small amounts in the livers of ducks at 16 embryonic days of age.The expression of IGF1 showed a continuous increase with the increase of embryonic age/age,IGF2 and IGF-ⅠR showed a trend of increasing and then decreasing.There was a significant positive correlation among IGF1,IGF2 and IGF-ⅠR,and there was a synergistic expression phenomenon of the three genes in the early development of ducks'liver.The expression of hepatic IGF1,IGF2 and IGF-ⅠR mRNA played an important role in the early development of ducks.
Cherry Valley broiler duckLiver developmentIGF geneIGF-ⅠR gene
万方数据
维普
