首页|一例鸭坦布苏病毒与鸭圆环病毒混合感染樱桃谷肉鸭的病例报告

一例鸭坦布苏病毒与鸭圆环病毒混合感染樱桃谷肉鸭的病例报告

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2023年8月,广西某养鸭场鸭子突发软脚、腿部肌肉震颤等神经症状,为探究该场鸭群致病病原,对该鸭场的患病鸭进行调查.剖检结果显示:患病鸭肝脏轻度肿大、质脆,呈黄褐色,肾脏肿大.病理切片显示:肝细胞胞质中可见微小圆形空泡,可见少量淤血;脾脏组织见较多细胞坏死,细胞核固缩.病原检测结果显示:鸭坦布苏病毒(DTMUV)、鸭圆环病毒(DuCV)为阳性,细菌及其他病原检测结果为阴性.序列分析发现,该场流行的DTMUV与SCS01毒株遗传距离最近,属于Cluster 2.1;DuCV与山东毒株YF180401遗传距离最近,属于DuCV-1型,确定该养殖场鸭群突然发病为DTMUV混合感染DuCV所致.这两种病毒都是临床中常见危害鸭群的病原,但混合感染情况却少有报道.该研究旨在为我国今后开展DTMUV和DuCV的检测和综合防控提供参考.
A Case Report on Mixed Infection of Duck Tembusu Virus and Duck Circovirus in Cherry Valley Ducks
In August 2023,ducks in a duck farm in Guangxi Province suddenly suffered from neurological symptoms such as limp feet and leg muscle trembling.In order to explore the pathogen of this disease,the ducks were investigated.The anatomy results showed that the liver was slightly enlarged,brittle,yellowish brown,and the spleen was enlarged.Pathological sections showed that there were small round vacuoles in the cytoplasm of hepatocytes and a small amount of congestion.Necrocytosis and karyopyknosis were seen in the spleen tissue.The pathogen detection results showed that duck Tembusu virus(DTMUV)and duck circovirus(DuCV)were positive,while bacteria and other pathogens were negative.The results of sequence analysis showed that the detected duck Tembusu virus was genetically closely related to the SCS01 strain,belonging to Cluster 2.1.The detected duck circovirus was genetically closely related to the Shandong YF180401 strain,belonging to DuCV-1.It was determined that the sudden onset of duck flocks in this farm was caused by duck Tembusu virus and duck circovirus.These two viruses are common infectious pathogens that harm ducks in clinical practice,but mixed infection has rarely been reported.This study provides references for the detection and comprehensive prevention and control of DTMUV and DuCV in China.

Duck tembusu virusDuck circovirusCo-infectionCherry valley ducks

潘彦林、张俊勤、孙敏华、徐志宏、廖明

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仲恺农业工程学院动物科技学院,广东广州 510225

广东省农业科学院动物卫生研究所/农业农村部禽流感等家禽重大疾病防控重点实验室/广东省畜禽疫病防治研究重点实验室,广东广州 510640

鸭坦布苏病毒 鸭圆环病毒 混合感染 樱桃谷肉鸭

国家重点研发计划国家自然科学基金青年基金广东省农业科技创新十大主攻方向"揭榜挂帅"项目(十四五)广东省动物疫病野外科学观测研究站项目

2022YFD1801000321026912022SDZG022021B1212050021

2024

广东畜牧兽医科技
广东省畜牧兽医学会 广东省农业科学院畜牧研究所 广东省农业科学院兽医研究所

广东畜牧兽医科技

影响因子:0.29
ISSN:1005-8567
年,卷(期):2024.49(3)