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猪附红细胞体病的诊断分析及治疗

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猪附红细胞体病是由猪附红细胞体引起的一种以贫血、黄疸、发热为特征的传染病,仔猪感染猪附红细胞体后会引起较高的死亡率.2022年8月底,山东省某规模化猪场仔猪出现大量急性死亡.为确诊发病原因,对送检的发病仔猪进行了剖检和实验室诊断,进一步通过血涂片检查和荧光定量PCR检测进行确诊.结果显示:发病仔猪剖检病变多呈黄染、败血性变化,心血涂片检查发现大量红细胞变形,呈星芒状、锯齿状和半月状等不规则形状,符合附红细胞体特征,荧光定量PCR检测结果为阳性,从而确认引起该规模猪场仔猪死亡的病因为猪附红细胞体感染.根据诊断结果针对性给药,5 d后该猪场疫情得到有效控制.该病例的诊断结合了经典检测方法和现代分子生物学方法,所提出的治疗方案对规模化猪场在防控附红细胞体方面具有一定参考意义.
Diagnosis and Treatment of Swine Mycoplasma
Eperythrozoonosis is an infectious disease caused by Eperythrozoon suis,which is characterized by anemia,jaundice and fever.At the end of August 2022,a number of piglets died in a large-scale pig farm in Shandong Province.In order to investigate the causation of the disease,the infected piglets were dissected and diagnosed in the laboratory,and further confirmed by blood smear examination and fluorescent quantitative PCR detection.The results showed that the pathological changes of autopsy were mostly yellow staining and septicemic changes.A large number of red blood cells were deformed in the shape of star,zigzag and half-moon,which were in line with the characteristics of Eperythrozoonosis.The fluorescent quantitative PCR test result was positive,which also confirmed that the disease in this pig farm was caused by eperythrozoon infection.According to the diagnosis results,diseased piglets were treated with drugs and the epidemic situation was effectively controlled 5 days later.The diagnosis of this case combines modern molecular biology methods and classical detection methods,and the proposed treatment scheme has certain reference significance for large-scale pig farms in the prevention and control of Eperythrozoon.

EperythrozoonosisLarge-scale farmDiagnosisTreatment schedule

蒋磊、刘源、李秀玲、杜兴乾、段连茂

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河北农业大学动物医学院,河北保定 071000

瑞东农牧(山东)有限责任公司,山东济南 250000

猪附红细胞体 规模化猪场 诊断 治疗方案

2024

广东畜牧兽医科技
广东省畜牧兽医学会 广东省农业科学院畜牧研究所 广东省农业科学院兽医研究所

广东畜牧兽医科技

影响因子:0.29
ISSN:1005-8567
年,卷(期):2024.49(3)