Objective To investigate the correlation between glycosylated hemoglobin(HbA1c),homocysteine(Hcy)and coronary artery lesions in middle-aged and elderly patients with acute coronary syndrome(ACS).Methods A total of 515 middle-aged and elderly patients with ACS were divided into single-vessel and multi-vessel groups according to coronary angiography,and mild and moderate/severe groups based on Gensini scores.The correlation between HbA1c,Hcy and coronary artery lesions was evaluated by Pearson correlation analysis.Results HbA1c and Hcy levels were lower in single-vessel and mild ACS groups than in multi-vessel and moderate/severe ACS groups(P<0.01 or 0.05).There were positive correlations between HbA1c and multi-vessel lesions(r=0.103,P<0.05)and between Hcy and moderate/severe ACS(r=0.164,P<0.01).Conclusion HbA1c and Hcy could be respectively contribute to multi-vessel lesions and moderate/severe ACS in middle-aged and elderly patients.
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