摘要
目的 利用多导睡眠监测(PSG)分析多系统萎缩(MSA)患者的睡眠障碍.方法 6例MSA患者和6例对照者进行PSG监测,比较两组总睡眠时间、睡眠效率、睡眠潜伏期、入睡后清醒时间、觉醒次数、各睡眠分期占比、微觉醒指数、呼吸暂停低通气指数(AHI)、睡眠周期性肢体运动指数(PLMSI)等指标.结果 MSA患者总睡眠时间和睡眠效率低于对照组(P＜0.01);入睡后清醒时间、浅睡眠N1期比例、微觉醒指数、AHI、PLMSI均高于对照组(P＜0.01或0.05).5例MSA患者出现快动眼睡眠肌张力失迟缓(RSWA),4例出现喘鸣,2例出现大喊大叫及拳打脚踢现象.结论 MSA患者存在较严重睡眠障碍.
Abstract
Objective To study the somnipathy in patients with multiple system atrophy(MSA)using polysomnography(PSG).Methods Six MSA patients and 6 healthy controls underwent PSG.Total sleep time,sleep efficiency,sleep latency,wake after sleep onset(WASO),awaking times,sleep stages,microarousal index,apnea-hypopnea index(AHI),and periodic limb movement of sleep index(PLMSI)were compared between two groups.Results Compared with control group,total sleep time and sleep efficiency were lower(P＜0.0l),while WASO,N1 light sleep,microarousal index,AHI,and PLMSI were higher in control group(P＜0.01 or 0.05).In addition,REM sleep dystonia,stridor and disturbed episodes occurred in 5,4 and 2 MSA patients.Conclusion There is a severe somnipathy in MSA patients.
基金项目
湖南省自然科学基金科卫联合项目(2021JJ70124)
长沙市卫生健康委科研项目(KJ-B2023048)
NETL
NSTL
万方数据