139例大血管性急性缺血性脑卒中患者卒中后抑郁程度及危险因素分析
Severity and risk factors of depression following acute ischemic stroke with large vessel occlusion
全洁 1林军 1关春红 1马志远 1陈国光 1龙亚德1
作者信息
- 1. 广东医科大学附属第二医院神经内科,广东湛江 524000
- 折叠
摘要
目的 了解大血管性急性缺血性脑卒中(AIS-LVO)后抑郁程度及危险因素.方法 分析 139 例AIS-LVO患者中AIS-LVO后抑郁发病率及程度,采用多因素logistic 回归分析其危险因素.结果 64 例(46.0%)患者发生抑郁,其中轻、中和重度分别占 29.7%、46.9%和 23.4%.入院时美国国立卫生研究院卒中量表(NIHSS)评分和超敏C反应蛋白(hs-CRP)水平、基底节或额叶病变是抑郁的独立危险因素(P<0.01 或 0.05).结论 AIS-LVO后抑郁以轻中度为主.入院时NIHSS评分和hs-CRP水平增高、基底节或额叶病变的AIS-LVO患者更易发生抑郁.
Abstract
Objective To analyze the severity and risk factors of depression following acute ischemic stroke with large vessel occlusion(AIS-LVO).Methods The incidence and severity of depression were analyzed in 139 AIS-LVO patients.The risk factors for depression were evaluated by multivariate logistic regression analysis.Results Depression occurred in 64(46.0%)cases,with 29.7%of mild,46.9%of moderate and 23.4%of severe depression.NIHSS and hypersensitive C-reactive protein(hs-CRP)on admission,and basal ganglia or frontal lobe lesions were independent risk factors for depression(P<0.01 or 0.05).Conclusion The depression following AIS-LVO is commonly mild and moderate.High NIHSS and hs-CRP levels on admission,and basal ganglia or frontal lobe lesions are more prone to develop depression in AIS-LVO patients.
关键词
大血管性急性缺血性脑卒中/抑郁/危险因素Key words
acute ischemic stroke with large vessel occlusion/depression/risk factors引用本文复制引用
基金项目
湛江市科技发展专项资金竞争性分配项目(2021A05098)
出版年
2024
NETL
NSTL
万方数据