摘要
纳米酶是一种具有酶活性的纳米材料.与天然酶和传统人工酶相比,具有稳定性好、成本低、理化性质易于调节等优点,在工业、医药、生物等领域有着广泛的应用.随着纳米酶的合成设计、活性验证、机制探索和应用等方面取得的成就,纳米酶已被广泛应用于肿瘤治疗领域并取得了良好的治疗效果.该文对纳米酶的不同分类和催化机理,及其在肿瘤治疗中的应用和发展方向作一综述,以期为研究更加合理、高效的肿瘤治疗模式奠定基础.
Abstract
Nanoenzymes are nanomaterials with enzymatic activity.Compared with natural enzymes and traditional artificial enzymes,it has the advantages of good stability,low cost,and easy adjustment of physicochemical properties,and has a wide range of applications in industry,medicine,biology and other fields.With the achievements in synthetic design,activity validation,mechanism exploration,and application of nanoenzymes,nanoenzymes have been widely used in the field of tumor therapy and achieved good therapeutic effects.This review provides an overview of the different classifications and catalytic mechanisms of nanoenzymes,as well as their applications and directions of development in tumor therapy,aiming at laying a foundation for the study of a more rational and efficient mode of tumor therapy.
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