摘要
目的 分析新型冠状病毒感染脆弱人群危险因素分析.方法 收集 201 名 60 岁及以上新冠肺炎脆弱患者的临床资料,分析住院死亡率的危险因素.结果 201 例 COVID-19 患者中存活 158 例(78.6%),死亡 43 例(21.4%).logistic回归分析示C反应蛋白(CRP)、磨玻璃样影、甘油三酯、血小板与淋巴细胞比值(PLR)、甘油三酯-葡萄糖指数(TyG)、血小板是院内死亡的独立影响因素(P<0.05).甘油三酯+CRP+磨玻璃影+血小板+PLR+TyG对脆弱人群院内死亡的预测价值:曲线下面积AUC为 0.914(95%CI:0.869~0.960,P<0.001),特异性为 0.744,敏感度为 0.943.结论 COVID-19 脆弱人群院内死亡率与甘油三酯、TyG、磨玻璃样影、CRP、PLR、血小板密切相关.
Abstract
Objective To analyze the risk factors for vulnerable COVID-19 patients.Methods Clinical data of 201 vulnerable COVID-19 patients aged 60 years or more were used to analyze the risk factors for hospitalization mortality.Results There were 158 survivals(78.6%)and 43 deaths(21.4%)of 201 cases.Logistic regression analysis showed C-reactive protein(CRP),ground-glass opacity(GGO),triglycerides,platelet/lymphocyte ratio(PLR),triglyceride-glucose index(TyG),and platelets were independent factors for hospital mortality(P<0.05).The area under the curve(AUC),specificity and sensitivity of triglycerides+CRP+GGO+platelets+PLR+TyG were 0.914(95%CI:0.869-0.960,P<0.001),0.744,0.943,respectively for hospital mortality.Conclusion The high hospital mortality of vulnerable COVID-19 patients is associated with triglycerides,TyG,GGO,CRP,PLR,and platelets.