广东医科大学学报2024,Vol.42Issue(6) :619-623.

健康老年人左室射血分数与多种冠心病危险因素的相关性分析

Correlation between left ventricular ejection fraction and various risk factors for coronary heart disease in healthy elderly population

赵征 吕悦
广东医科大学学报2024,Vol.42Issue(6) :619-623.

健康老年人左室射血分数与多种冠心病危险因素的相关性分析

Correlation between left ventricular ejection fraction and various risk factors for coronary heart disease in healthy elderly population

赵征 1吕悦1
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作者信息

  • 1. 河南大学淮河医院超声科,河南 开封 475000
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摘要

目的 探讨老年人左室射血分数(LVEF)水平与多种冠心病危险因素的相关性.方法 324 例心脏多普勒超声测定均未发现明确的器质性心脏疾病的老年人根据LVEF值,将LVEF<50%者设为LVEF下降组(n=130),LVEF≥50%者设为LVEF正常组(n=194).比较两组吸烟史、肥胖、低密度脂蛋白胆固醇(LDL-C)、高血压病和 2 型糖尿病等冠心病危险因素数据,应用皮尔逊线性相关、多因素Logistic回归分析评估LVEF与以上危险因素的相关性.结果 皮尔逊线性相关分析显示LVEF与LDL-C水平呈负相关(r=-0.336,P<0.001).多因素logistic回归分析发现吸烟史、肥胖、LDL-C高水平与LVEF降低存在显著相关性(P<0.001 或 0.05).结论 老年人LVEF下降与吸烟史、肥胖和LDL-C升高有关.

Abstract

Objective To investigate the correlation between left ventricular ejection fraction(LVEF)and multiple risk factors for coronary heart disease(CHD)in elderly population.Methods According to 50%cutoffof LVEF value,324 elderly subjects without structural heart disease using echocardiography were divided into normal(n=194)and low(n=130)LVEF groups.The correlation between LVEF and CHD risk factors including smoking,obesity,low-density lipoprotein cholesterol(LDL-C),hypertension and type 2 diabetes were analyzed by Pearson linear correlation and multivariate logistic regression in both groups.Results Pearson linear correlation analysis showed a negative correlation between LVEF and LDL-C level(r=-0.336,P<0.001).Multivariate logistic regression analysis revealed that smoking,obesity and high LDL-C level were significantly correlated with low LVEF(P<0.001 or 0.05).Conclusion Low LVEF is associated with smoking,obesity and elevated LDL-C in the elderly.

关键词

左室射血分数/冠心病/危险因素/老年

Key words

left ventricular ejection fraction/coronary heart disease/risk factors/elderly population

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出版年

2024
广东医科大学学报
广东医学院

广东医科大学学报

影响因子:0.828
ISSN:1005-4057
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