Progress on Influence of Composition of α-L-Guluronic Acid and β-D-Mannuronic Acid on Structural and Properties of Alginate
Alginate is mainly composed of α-L-guluronic acid(G)and its differential isomer β-D-mannuronic acid(M),and the content,distribution,and spatial structure of the two units directly determine the properties of alginate.In order to clarify the influence of the structural differences of the two glucuronic acid units on the structural properties of glucuronic acid oligomers and polymers,the preparation methods and structural characteristics were analyzed,focused on the solubility,solution rheology,stability,ion exchange,gel properties and biological activity of alginate with different glucuronic acid compositions and distributions,and the influence of different M/G ratios on the properties of alginate fibers and effects of medical dressings were analyzed.The results provide a reference for advancing the further application of alginate macromolecules in medical,sanitary and textile industries.