Research Progress of Drug Loaded Silicone Hydrogel Contact Lenses
The drug-loaded contact lens can effectively prolong the drug release time and improve the bioavailability of drugs,which is an ideal way of ocular drug delivery.At present,in the field of vision correction,silica-based hydrogel contact lenses have been widely used instead of traditional hydrogel-based contact lenses because of their advantages of high oxygen permeability and low water content,and have broad application prospects in the field of ophthalmic treatment and prevention.This review focuses on the research progress of drug-loaded silica-based hydrogel contact lenses in recent years.According to different drug-loading methods,the structure of silica-based hydrogel substrate,drug types,drug release mechanism and other aspects were analyzed in detail,and the development was prospected.
Silica-based hydrogelContact lensDrug loading modeMechanism of drug sustained release
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