Research Progress on Natural Polymer Antibacterial Hydrogel Wound Dressings
Natural polymers,such as polysaccharides and proteins,are abundant in nature,boasting abundent functional groups that lend themselves readily to modify.Some natural polymers also exhibit inherent antibacterial properties,alongside unique biological attributes.Hydrogels derived from natural polymers typically demonstrate excellent biocompatibility,degradability,and hydrophilicity,owing to their three-dimensional structure which provides an ideal reservoir for antibacterial agents.These attributes confer a distinct advantage upon natural polymers in the formulation of antibacterial hydrogel dressings.Beyond material selection,the choice of crosslinking strategy is pivotal.This work summarizes recent methodologies for the preparation of natural polymer antibacterial hydrogel dressings,encompassing chemical,physical,and hybrid crosslinking techniques.Based on their antibacterial attributes,hydrogels are categorized into two classes:those with inherent antibacterial properties and those laden with antibacterial agents.Detailed accounts are provided regarding the application and potential of these hydrogel dressings in medical,healthcare,and allied domains.Lastly,the extant research bottlenecks are analyzed and the future development for natural polymer antibacterial hydrogels is prospected.
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