摘要
DNA是构成生命基础的最重要分子,DNA是否导电以及怎样导电,关系到我们对生命信号的传递、和对生命和生命现象的深入理解和揭示,以及可编程DNA分子电子学的发展,国际科技界一直高度关注,近二十年来也一直是研究的热点和难点.然而,DNA是一个复杂的体系,其导电性问题仍然不清楚,备受争议.本综述中,我们简述了DNA导电性问题的研究历史,分析了DNA导电性问题争议的主要原因,总结了DNA导电性研究中存在的主要问题,其主要归因于测量方法的多样性和DNA分子的复杂性.最后,对DNA导电性研究的未来发展方向进行了展望,DNA导电性在生命信号传递、生物传感器、分子电子学等领域具有巨大的应用潜力,其研究也将为生物科学和电子学的融合提供新思路.
Abstract
DNA is the most important molecule for forming the basis of life.Whether and how DNA conducts electricity is highly related to the understanding and revelation of the transmission of life signals and life phenomena,as well as the development of programmable DNA molecular electronics.Thus,this topic has attracted tremendous attention worldwidely.However,DNA is a complex system that its conductivity property is still unclear and controversial.In this review,we briefly summarize the research history of DNA conductivity,analyze the main reasons for the controversy on DNA conductivity.The main problems existing in the study of DNA conductivity are mainly attributed to the diversity of measurement methods and the complexity of the DNA molecule.Finally,we propose the future development direction of DNA conductivity research.DNA conductivity has huge application potential in the fields of life signal transmission,biosensors,molecular electronics,etc.The research on DNA conductivity will also provide new ideas for the integration of biological science and electronics.
维普
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