Strategies and Applications of Cell Membrane Surface Functionalization of Polymer Materials
The cell membrane,the outer protective structure of a cell,serves to shield its internal components from external disruptions.By manipulating the cell membrane and incorporating specific molecules or structures,one can exert control over the fate and functionality of cells,thereby imbuing them with specialized functions.In recent years,the strategy of using biomacromolecules to self-assemble on cell membranes has been widely studied for functionalizing the surface of cell membranes.This paper reviews that the self-assembly of different biomacromolecules on the cell membrane surface can change the biological effects of cells and produce positive effects in tumor immunotherapy.It is elaborated that when biomacromolecular materials are self-assembled on the cell membrane,it can cause biological effects of cells,such as oligomerization of cell membrane receptor proteins to activate immune cells,changing cell membrane permeability to promote endocytosis,etc.At the same time,its application in tumor treatment is briefly introduced,and the future development of self-assembly technology modified cell membrane surface is prospected.
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