影像科学与光化学2025,Vol.43Issue(1) :3-9,16.DOI:10.7517/issn.1674-0475.2025.01.01

钆塞酸二钠增强MRI在结直肠癌肝转移瘤精准诊断与治疗评估中的临床应用及前沿进展

Clinical Application and Advanced Progress of Gd-EOB-DTPA Enhanced MRI in Accurate Diagnosis and Treatment Evaluation of CRLM

李书琪 朱绍成
影像科学与光化学2025,Vol.43Issue(1) :3-9,16.DOI:10.7517/issn.1674-0475.2025.01.01

钆塞酸二钠增强MRI在结直肠癌肝转移瘤精准诊断与治疗评估中的临床应用及前沿进展

Clinical Application and Advanced Progress of Gd-EOB-DTPA Enhanced MRI in Accurate Diagnosis and Treatment Evaluation of CRLM

李书琪 1朱绍成1
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作者信息

  • 1. 郑州大学人民医院 医学影像科,河南 450003;河南省人民医院医学影像科,河南 450003
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摘要

钆塞酸二钠(gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid,Gd-EOB-DTPA)作为肝胆特异性对比剂,在肝脏局灶性病变的磁共振成像(magnetic resonance imaging,MRI)检查中扮演着日益重要的角色.本研究综述了Gd-EOB-DTPA增强MRI技术在早期发现、精确诊断结直肠癌肝转移瘤(colorectal liver metastases,CRLM)以及评估治疗反应方面的应用现状和最新进展.Gd-EOB-DTPA的引入显著提高了对CRLM的检测敏感性,尤其是在直径≤1cm的小病变中.此外,基于Gd-EOB-DTPA增强MRI的影像组学为CRLM的评估提供了新的视角,通过定量分析影像特征,辅助临床决策.本文归纳总结了Gd-EOB-DTPA增强MRI在CRLM诊疗中的特异性影像表现及优势,为进一步优化患者管理和指导治疗策略提供了科学依据.

Abstract

Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(Gd-EOB-DTPA),as a hepatobiliary specific contrast agent,plays an increasingly important role in magnetic resonance imaging(MRI)of focal hepatic lesions.This study reviewed the application status and latest progress of Gd-EOB-DTPA enhanced MRI technology in early detection,accurate diagnosis and evaluation of response to treatment of colorectal liver metastases(CRLM).The introduction of Gd-EOB-DTPA significantly improved the detection sensitivity of CRLM,especially in small lesions with a diameter of less than 1 cm.In addition,radiomics based on Gd-EOB-DTPA enhanced MRI provides a new perspective for the evaluation of CRLM and assists clinical decision making through quantitative analysis of image features.This paper summarizes the specific image features and advantages of Gd-EOB-DTPA enhanced MRI in the diagnosis and treatment of CRLM,which provides a scientific basis for further optimizing patient management and guiding treatment strategies.

关键词

钆塞酸二钠/肝转移瘤/磁共振成像/结直肠癌/影像组学

Key words

Gd-EOB-DTPA/liver metastases/magnetic resonanceimaging/colorectalcancer/radiomics

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出版年

2025
影像科学与光化学
中国科学院理化技术研究所 中国感光学会

影像科学与光化学

CSTPCD
影响因子:0.287
ISSN:1674-0475
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