3.0 T MRI Dynamic Enhancement Plus Multiple B-value DWI in the Differentiation of Benign and Malignant Lymph Nodes in Rectal Cancer and its Correlation with Vascular Invasion
Objective:To evaluate the application value of 3.0T magnetic resonance imaging(MRI)techniques,including dynamic contrast-enhanced imaging(DCE)and multiple-B-value diffusion-weighted imaging(DWI),in differentiating benign and malignant lymph nodes of rectal cancer,and to explore the correlation between imaging parameters and vascular invasion of rectal cancer.Methods:The clinical data of 122 patients with rectal cancer in our hospital from March 2021 to March 2023 were analyzed retrospectively.All patients were examined by 3.0T DCE-MRI and multi-B-value DWI.The diagnostic efficacy of DCE-MRI and multi-B-value DWI was compared with conventional MRI in differentiating lymph node properties of rectal cancer,and the correlation between imaging parameters and vascular invasion status was analyzed.Results:Among 122 patients,43 cases(35.25％)were malignant lymph nodes and 79 cases(64.75％)were benign lymph nodes.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of DCE-MRI and multi-B-value DWI in diagnosing lymph node properties of rectal cancer were higher than those of conventional MRI(P＜0.05).In addition,the T stage,CEA level,Ktrans value and Kep value of the vascular invasion positive group were significantly higher than those of the negative group,while the ADC value was lower(P＜0.05).Logistic regression analysis showed that high ADC value was negatively correlated with vascular invasion,while high T stage,CEA level,Ktrans value and Kep value were positively correlated with vascular invasion(P＜0.05).ROC curve analysis showed that ADC value,Ktrans value and Kep value had certain value in predicting vascular invasion of rectal cancer(AUC was 0.791,0.848 and 0.874,respectively).Conclusion:DCE-MRI and multi-B-value DWI show high diagnostic efficiency in differentiating benign and malignant lymph nodes of rectal cancer,and these imaging parameters are closely related to the existence of vascular invasion.In particular,ADC value,Ktrans value and Kep value can effectively predict the risk of vascular invasion in patients with rectal cancer,which provides important reference for clinical treatment decision-making.
万方数据
维普
