Time-series study on the impact of atmospheric fine particulate matter PM2.5 on short-term pulmonary function in elderly patients with chronic obstructive pulmonary disease in Taiyuan City
Objective To explore the effect of fine particulate matter(PM2.5)in Taiyuan City on short-term pulmonary function in elderly patients with chronic obstructive pulmonary disease(COPD).Methods Among the 1 015 elderly COPD patients admitted to the respiratory departments of five general hospitals in Taiyuan City from December 2021 to December 2023 were retrospectively selected for research;medical records,air pollutant data and meteorological data were analyzed;the relationship between PM2.5 and lung function indicators and air pollutants was analyzed;the impact of PM2.5 on lung function and its lag effect were analyzed;the cumulative effect of PM2.5 concentration on the risk of pulmonary ventilation dysfunction was analyzed;The influence of gender and age on the relationship between PM2.5 and patients'short-term pulmonary function was analyzed.Results PM2.5,respirable particulate matter(PM10),sulfur dioxide(SO2),carbon monoxide(CO)were negatively correlated with average temperature and average humidity(P＜0.05);Nitrogen dioxide(NO2),ozone(O3)were negatively correlated with average temperature(P＜0.05);There was a positive correlation among PM2.5,PM10,SO2,CO,NO2,and O3(P＜0.05);Elevated PM2.5 is an independent risk factor for decreased lung function and increased air pollutants(P＜0.05);At lag0 and lag1,PM2.5 concentration was negatively correlated with lung function in a dose-response manner(P＜0.05);daily average PM2.5 concentration at lag0 was a dangerous effect(P＜0.05).Conclusion The impact of PM2.5 concentration on lung function has a certain time lag.An increase in PM2.5 concentrations can lead to a decline in lung function.
PM2.5ElderlyChronic obstructive pulmonary diseaseLung functionTime series
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