Epidemiological Characteristics and Risk Factors of Non-alcoholic Fatty Liver Disease in Jincheng between 2015 and 2020
Objective To investigate the epidemiological characteristics and risk factors of non-alcoholic fatty liver disease in Jincheng between 2015 and 2020.Methods Clinical data of 8 578 medical check-ups at Physical Examination Center of ou hospital from January 2015 to December 2020 were retrospectively selected.The prevalence of non-alcoholic fatty liver disease in the last 5 years was recorded,and Logistic regression was utilized to identify the risk factors for the development of non-alcoholic fatty liver disease.Results The overall prevalence of non-alcoholic fatty liver disease in Jincheng was 14.57％in 2015-2020.The prevalence of non-alcoholic fatty liver disease was higher in men than in women(16.99％vs 10.98％)and highest in the 40-59 age group(18.76％).No statistical difference was reported in blood urea nitrogen(BUN)and serum creatinine(Scr)between groups(P＞0.05),while statistical difference was found in diabetes,hypertension,body mass index(BMI),waist circumference,weekly exercise frequency,daily vegetable intake,triglycerides(TG),total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),alanine aminotransferase(ALT)and uric acid(UA)between two groups(P＜0.05).Multivariate Logistic regression analysis denoted that BMI(OR=2.794,95％CI:1.745-4.550),waist circumference(OR=2.586,95％CI:1.585-4.299),diabetes(OR=0.644,95％CI:1.425-2.781),hypertension(OR=1.479,95％CI:1.121-2.290),weekly exercise ≥6h(OR=0.617,95％CI:0.519-0.709),daily vegetable intake ≥ 300g(OR=0.590,95％CI:0.467-0.652),TG(OR=1.481,95％CI:1.122-1.996),TC(OR=1.562,95％CI:1.143-2.135),LDL-C(OR=1.440,95％CI:1.139-2.048),HDL-C(OR=0.656,95％CI:0.587-0.783),ALT(OR=1.591,95％CI:1.056-2.183),and UA(OR=1.412,95％CI:1.009-1.887)were risk factors for non-alcoholic fatty liver disease(P＜0.05).Conclusion The prevalence of non-alcoholic fatty liver disease in Jincheng City from 2015 to 2020 is 14.57％,the prevalence of males is higher than that of females,and the prevalence rate is the highest in the 40-59 age group.Moreover,diabetes mellitus,hypertension,BMI,waist circumference,weekly exercise,daily vegetable intake,serum TG,TC,LDL-C,HDL-C,ALT,and UA are all associated with the risk of the disease.
Non alcoholic fatty liver diseaseEpidemiological characteristicsLogistic regressionRisk factor
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