首页|环境化学物暴露与急性淋巴细胞白血病关系的研究进展

环境化学物暴露与急性淋巴细胞白血病关系的研究进展

扫码查看
急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)是一种常见的血液系统恶性肿瘤,其恶性程度高,危害大,且复发率较高,加之治疗过程复杂,治疗费用高,不仅给患者带来极大的痛苦,还增加了患者家庭,乃至社会的经济负担.关于ALL发病机制目前尚无定论,但据研究发现,环境因素与遗传因素在ALL发病中可能发挥着重要作用.故本文总结近年有关环境化学暴露因素与ALL表观遗传研究的报道,试综述环境化学物暴露与ALL发病机制的关系,为临床研究提供参考思路.
Research progress on relationship between environmental chemical exposure and acute lymphoblastic leukemia
Acute lymphoblastic leukemia(ALL)is a common hematological malignant tumor with high malignancy,great harm and high recurrence rate.In addition,the treatment process of ALL is complicated and the treatment cost is high,which not only brings great pain to patients,but also increases the economic burden of patients'families and even society.The pathogenesis of ALL is still inconclusive,but studies have found that environmental factor and genetic factor may play an important role in the pathogenesis of ALL.Therefore,this paper summarizes the reports on environmental chemical exposure factors and ALL epigenetics studies in recent years,and tries to review the relationship between environmental chemical exposure and pathogenesis of ALL,so as to provide reference ideas for clinical research.

Environmental chemical exposureAcute lymphoblastic leukemiaEpigenetics

王利、王科进

展开 >

成都上锦南府医院血液内科,四川成都 610000

环境化学物暴露 急性淋巴细胞白血病 表观遗传

2025

公共卫生与预防医学
湖北省预防医学会,中华预防医学会,湖北省疾病预防控制中心

公共卫生与预防医学

影响因子:1.399
ISSN:1006-2483
年,卷(期):2025.36(1)