Epidemiological characteristics and influencing factors of lung cancer in Quanshan District of Xuzhou City
Objective To explore the epidemiological characteristics of lung cancer in Quanshan District of Xuzhou cityand analyze the influencing factors,so as to provide theoretical guidance for the prevention and control of lung cancer in Quanshan District of Xuzhou City.Methods A total of 302 patients with lung cancer diagnosed in the Affiliated Hospital of Xuzhou Medical University were selected as case group from January 2019 to December 2023,and 300 healthy persons were selected as control group,a self-designed questionnaire was used to investigate the general and clinical information of the patients,and Logistic regression was used to analyze the risk factors.Results There were a statistically difference in two groups for the smoking index(x2=40.058,P＜0.001),Chemical occupational environment(x2=28.153,P＜0.001),weekly exercise mode(x2=11.021,P=0.004),emphysema score(x2=142.812,P＜0.001).In addition,the CA125 in the case group was(87.11±13.09)U/mL,while the control group was(16.32±5.61)U/mL,with a statistically difference(t=34.581,P＜0.001).The logistic regression results showed that smoking index ≥20 cigarettes per day(OR=3.448,P=0.021),chemical occupational environment(OR=4.091,P＜0.001),emphysema score(OR=1.302,P＜0.001)or severe(OR=1.461,P＜0.001),and CA125 detection value≥75U/mL(OR＞1.6,P＜0.001)were independent risk factors for lung cancer,while moderate weekly exercise(OR=0.821,P＜0.001)was a protective factor for lung cancer.Conclusion Smoking,high CA125 index,chemical occupational environment,and long-term emphysema are risk factors for the occurrence of lung malignant tumors in Quanshan District of Xuzhou City,screening regularly of CA125 in people who have smoking,emphysema,and being chemical occupational environment should be strengthened,and appropriate health education in proper exerciseshould be provided to prevent and reduce the incidence of lung malignant tumors.
万方数据
维普
